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Chemical Name: Estradiol
Vagifem (Estradiol) is a female hormone and is usually given to women who no longer produce the proper amount.Vagifem (Estradiol) is used to reduce menopause symptoms (e.g., vaginal dryness). Vagifem (Estradiol),the only vaginal estrogen tablet, can improve symptoms of atrophic vaginitis during menopause.
Vagifem (Estradiol) is the only tablet containing estrogen that is easily inserted into your vagina with the preloaded applicator. The Vagifem (Estradiol) tablet dissolves gradually, releasing estrogen into the walls of the vagina, where Vagifem (Estradiol) is needed. When used as directed, Vagifem (Estradiol) is clinically proven to relieve the symptoms and discomfort of atrophic vaginitis, including dryness, soreness, and irritation. It may take 2-12 weeks to gain full benefits of Vagifem (Estradiol).
Other local medications placed directly into the vagina for atrophic vaginitis, such as creams, are often very messy and may leak onto undergarments and bed sheets. The estrogen contained in Vagifem (Estradiol) is derived from plants and is identical to the estrogen that your body produces naturally. You can take comfort in knowing that the type of estrogen in Vagifem (Estradiol) has been used by millions of women worldwide in a variety of health care products, including oral contraceptives and oral hormone therapy (HT). Oral doses of estrogen may not produce blood levels high enough to adequately treat symptoms associated with atrophic vaginitis.
Taking Vagifem (Estradiol) is easy. Using the disposable applicator, gently insert 1 Vagifem (Estradiol) tablet into your vagina daily for the first 2 weeks. After that insert 1 tablet 2 times a week as directed by your doctor.Vagifem (Estradiol) can be inserted at any time of the day but should be inserted at the same time every day.
Vagifem (Estradiol) works very quickly. Your symptoms may begin improving within the first 2 weeks of use. However, it may take up to 12 weeks to feel the full benefits of Vagifem (Estradiol).
Vagifem Side Effects:
Vagifem side effects, that may go away during treatment, include dizziness, lightheadedness, headache, stomach upset, bloating, nausea, weight changes, increased/decreased interest in sex, or breast tenderness. If Vagifem side effects continue or are bothersome, check with your doctor. CONTACT YOUR DOCTOR IMMEDIATELY if you experience Vagifem side effects like mental/mood changes (e.g., severe depression), calf/pain swelling, sudden severe headache, chest pain, trouble breathing, one-sided weakness, slurred speech, vision changes (e.g., change in contact lens fit, loss of vision), breast lumps, swelling of hands/feet, changes in vaginal bleeding (e.g., spotting, breakthrough bleeding, or prolonged bleeding), unusual vaginal discharge/itching/odor, or yellowing of the eyes/skin. Vagifem side effects are unlikely, but seek immediate medical attention if Vagifem side effects occur. Symptoms of Vagifem side effects include rash, itching, swelling, severe dizziness, or trouble breathing. If you notice other Vagifem side effects not listed above, contact your doctor, nurse, or pharmacist.
Vagifem WARNING & Vagifem Information: Estrogens have been reported to increase the chance of womb (endometrial) cancer in women who have been through menopause, especially in women with a uterus who receive estrogen-only hormone therapy. Estrogens may also increase the risk of cancer of the ovary/breast. Estrogen-containing medicines should not be used to prevent heart disease. Estrogen given in combination with another hormone (progestin) for replacement therapy can infrequently cause heart disease (e.g., heart attacks), stroke, serious blood clots, and cancer of the breast. These risks appear to depend on the length of time this medicine is used and the amount of estrogen per dose. Therefore, this medicine should be used for the shortest possible length of time at the lowest effective dose, so you obtain the benefits and minimize the chance of serious side effects from long-term treatment. Consult your doctor or pharmacist for details. If you use this medicine for an extended period, you should be evaluated at least once yearly (see CAUTIONS section). This medicine is not effective in preventing/treating a tendency toward miscarriages nor the threat of miscarriage. This medicine must not be used during pregnancy because its use may result in birth defects or cancer later in the child's life (see CAUTIONS section). INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are using other vaginal medicines. DO NOT START OR STOP ANY MEDICINE without doctor or pharmacist approval. Inform your doctor of any other medical conditions including a family medical history (e.g., especially breast lumps/cancer), asthma, diabetes, seizures, migraine headaches, liver or kidney disease, heart disease (e.g., high blood pressure, heart attacks, congestive heart failure), low thyroid hormone (hypothyroidism), abnormal calcium level in the blood, depression, high blood pressure during pregnancy, yellowing of eyes/skin during pregnancy or with past estrogen use, womb problems (e.g., uterine fibroids/endometriosis), cholesterol/lipid problems, gallbladder disease, excessive weight gain, certain blood disorder (porphyria), allergies, pregnancy, or breast-feeding. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have certain medical conditions including undiagnosed abnormal vaginal bleeding, certain cancers (e.g., breast cancer, especially non-metastatic type), blood clots, or active/recent stroke or heart attack. Contact your doctor or pharmacist if you have any questions or need more Vagifem Information.
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