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Chemical Name: Indinavir Sulfate

Please select Dosage and Quantity
  Product Manufacturer Country Dosage Quantity Price($USD)    
Crixivan  Brand United Kingdom 400 mg 180 $425.00
Indinavir Sulfate  Generic India 400 mg 90 $79.00

Crixivan Information:

Crixivan is a protease inhibitor used in combination with other anti-HIV drugs for the treatment of HIV. HIV causes the immune system to break down so that it can no longer fight off other infections. This leads to the fatal disease known as acquired immune deficiency syndrome (AIDS).Crixivan can help reduce your chances of getting illnesses associated with HIV. Crixivan can also help lower the amount of HIV in your body (called viral load) and raise your CD4 (T) cell count, but does not cure HIV or AIDS. Crixivan prevents T-cells that have been infected with HIV from producing new HIV. Crixivan can be taken alone or in combination with other HIV drugs such as Retrovir. Because Crixivan and Retrovir attack the virus in different ways, the combination is likely to be more effective than either drug alone.
Crixivan can be taken either three times a day or twice a day: The three-times-daily Crixivan dosing schedule involves taking two 400mg capsules every eight hours. If this dose is used, Crixivan should be taken on an empty stomach, meaning that you should not eat within two hours before or one hour after taking Crixivan. Alternatively, three-times-daily Crixivan can be taken with a light snack that does not contain fat (e.g., butter or milk). The more commonly used twice-daily Crixivan dosing schedule involves taking two 400mg capsules every 12 hours in combination with low doses of Norvir, another protease inhibitor. Norvir increases the amount of many HIV/AIDS drugs in the bloodstream, including Crixivan. This has a few advantages: it reduces the number of times a day Crixivan needs to be taken and eliminates the need to take Crixivan on an empty stomach. Because of these advantages, many doctors prefer to prescribe twice-daily Crixivan/Norvir instead of three-times-daily Crixivan (without Norvir).

Crixivan Side Effects:

Do not take Crixivan if you have had a serious allergic reaction to Crixivan or any of its components.
Some patients treated with Crixivan developed kidney stones. For some, this leads to more severe kidney problems, including kidney failure, inflammation of the kidneys, or kidney infection, which sometimes spreads to the blood. Drinking at least six 8-ounce glasses of liquid (preferably water) each day should help reduce the chance of forming a kidney stone.
Also, some patients experienced rapid breakdown of red blood cells (hemolytic anemia), which in some cases was severe or resulted in death; some had liver problems, including liver failure and death.
Diabetes and high blood sugar (hyperglycemia) have occurred in patients taking protease inhibitors. In some of these patients, this led to ketoacidosis, a serious condition caused by poorly controlled blood sugar. Some patients had diabetes before starting protease inhibitors; others did not. Some patients required adjustments to their diabetes medication. Others needed new diabetes medication.
Severe muscle pain and weakness have occurred in patients taking protease inhibitors, including Crixivan, together with some of the cholesterol-lowering medicines called “statins.” Call your doctor if you develop severe muscle pain or weakness.
Changes in body fat have been seen in some patients taking antiretroviral therapy. These changes may include increased amount of fat in the upper back and neck (“buffalo hump”), breast, and around the trunk. Loss of fat from the legs, arms, and face may also happen. The cause and long-term effects of these conditions are not known at this time.
Increases in bilirubin, a pigment in the liver (one laboratory test of liver function) have occurred in approximately 14% of patients, and, on rare occasions, a patient may develop yellowing of the skin and/or eyes.
Side effects occurring in 2% or more of patients included abdominal pain, fatigue or weakness, low red blood cell count, flank pain, painful urination, feeling unwell, nausea, upset stomach, diarrhea, vomiting, acid regurgitation, increased or decreased appetite, back pain, headache, dizziness, taste changes, rash, itchy skin, yellowing of the skin and/or eyes, upper respiratory infection, dry skin, and sore throat.

The generic alternative is not manufactured by the company that makes the brand product.

All prices are in US dollars.

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